Kimberly Raab-Graham

Kimberly Raab-Graham, PhD Principal Investigator

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Address

Where to find us:
100 E 24th St., NHB 3.320
Austin, TX 78705
512-232-8152

Mailing Address:
Raab-Graham Lab
The Center for Learning & Memory
The University of Texas at Austin
1 University Station Stop C7000
Austin, TX 78712-0805

Discover Molecular Mechanisms utilized during Learning and Memory

My group focuses on how synapses remodel their protein composition in a site-specific manner in response to changes in neuronal activity. Specifically, we study how NMDAR/mTOR signaling shifts the regional distribution (i.e. soma, dendrites, axons, etc) of proteins through changes in protein trafficking, local protein synthesis, or protein stability. We seek to understand the ways in which dynamic changes in ion channel and receptor density may influence synaptic integration and the threshold for neuronal firing. Furthermore, we want to discover how these cellular mechanisms are manipulated in mental disorders and neurodegenerative diseases.