Dr. Dan Johnston and his graduate student Sachin Vaidya have published a research article in Nature Neuroscience entitled “Temporal synchrony and gamma to theta power conversion in the dendrites of CA1 pyramidal neurons”. This work reveals the role of dendritic HCN channels in pyramidal neurons in transforming spatially distributed excitatory synaptic input into a coherent neuronal […]

Dr. Alison Preston recently published two papers in Current Biology.  A review article entitled “Interplay of the hippocampus and prefrontal cortex in memory” and an empirical paper entitled “Decoding the brain’s algorithm for categorization from its neuronal implementation”

Kevin Bieri, MD/PhD student in the Colgin Lab, received a Ruth L. Kirschstein NRSA award from NIMH for his project titled “Information Routing in the Hippocampus via Gamma Oscillations”.  This project will use electrophysiological recordings in freely behaving rats to determine the functional roles of two distinct variants of hippocampal gamma oscillations. This work will help […]

Dr. Marie Monfils published a paper in Learning & Memory entitled “Learned together, extinguished apart: Reducing fear to complex stimuli”(In press). This work examines how compound memories are encoded and extinguished, and reveals important implications for treatment of post-traumatic stress disorder.

Dr. Kim Raab-Graham received a grant from the Integrated Neuroscience Initiative Consortium on Alcoholism to support her pilot project that will study the potential role of changes in mTOR dependent protein synthesis as a result of excessive alcohol consumption.  These studies will help define the molecular targets involved in tolerance, physical dependence, and craving as a result of […]

Dr. Dan Johnston renewed his NIH RO1 grant entitled “Cellular Information Processing in the Hippocampus”. This project will explore common neurobiological mechanisms in animal models for depression and epilepsy by focusing on an ion channel (the h channel) that has been associated with both diseases.

Michael Mack, postdoctoral fellow in the Preston Lab, received a Ruth L. Kirschstein NRSA award from NIMH for his project titled “The mutual influence of attention and learning during knowledge acquisition”. Using a novel methodology combining functional magnetic resonance imaging and formal computational modeling, this project will investigate the neurobiological mechanisms that capture experiences and […]

Dr. Ila R Fiete has published the following paper in Nature Neuroscience.  “Specific evidence of low-dimensional continuous attractor dynamics in grid cells”, Yoon, KJ, Buice, MA, Barry, C, Hayman, R, Burgess, N, Fiete, IR (2013) http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.3450.html  

Dr. Laura Colgin published an Annual Review of Neuroscience article entitled “Mechanisms and functions of theta rhythms”.  This article reviews progress in the field of theta rhythm research in the brain, including how they support cognitive function and learning.  Annual Review Neuroscience, 36:295-312

Dr. Dan Johnston was invited to give a lecture at the National Institute of Child Health and Human Development scientific retreat for the division of Intramural Research.  He presented his research in the area of denderitic channelopathies.