PUBLICATIONS

2023

Witten, G., DeMott, E., Huang, G.,  Zelasko, F., de Jesus, B., Mulchand, C., Schuck, L., Pullman, S., Perez, A., Mahableshwarkar, P., Wu, Z., Cardona, E.A., Pierce, J.T., Dickinson, D.J., and Doonan, R. (2023). mScarlet and split fluorophore mScarlet resources for plasmid-based CRISPR/Cas9 knock-in in C. elegans. microPublication Biology. DOI: 10.17912/micropub.biology.000871.

Rubenzer, K.N., Pierce, J.T. (2023). Experiential diversity training and science learning for college students alongside peers with intellectual and developmental disabilities.  PLoS Biol. 21(6):e3002147. doi: 10.1371/journal.pbio.3002147

 

2022

Clites, B.L., Hofmann, H.A., Pierce, J.T. (2022). The promise of an evolutionary perspective of alcohol consumption. Neuroscience Insights. In press. Preprint DOI: 10.32942/osf.io/v23wj

Guzman, D.M., Chakka, K., Shi, T., Marron, A., Fiorito, A.E., Rahman, N.S., Ro, S., Sucich, D.G., Pierce, J.T. (2022). Transgenerational effects of alcohol on intoxication sensitivity in Caenorhabditis elegans. PLoS ONE 17(10): e0271849. doi.org: 10.1371/journal.pone.0271849
 

2021

Pierce, J.T., Rubenzer, K.N., Shetron, T.H. (2021). Reverse-Inclusion Continuing Education Program at College Aimed at Students with Intellectual and Developmental Disabilities: Program Implementation. EdArXiv, doi: 10.35542/osf.io/frxaq.
 

2020

Sae-Lee, W., Scott, L.L., Brose, L., Encarnacion, A.J., Shi, T., Kore, P., Oyibo, L.O., Ye, C., Rozmiarek, S.K., Pierce, J.T. (2020). APP-induced Patterned Neurodegeneration Exacerbated by APOE4 in Caenorhabditis elegans. G3 Genes|Genomes|Genetics, 10(6), doi: 10.1534/g3.120.401486.
 
Cohn, J.A., Cebul, E.R., Valperga, G., Brose, L., de Bono, M., Heiman, M.G., and Pierce, J.T. (2020). Long-term Activity Drives Dendritic Branch Elaboration of a C. Elegans Sensory Neuron. Developmental Biology, 461(1):66-74. doi: 10.1016/j.ydbio.2020.01.005.
 

2019

Cohn, J., Dwivedi, V., Valperga, G., Zarate, N., de Bono, M., Horvitz, H.R., and Pierce, J.T. (2019). Activity-Dependent Regulation of the Proapoptotic BH3-Only Gene egl-1 in a Living Neuron Pair in Caenorhabditis elegans. G3 Genes|Genomes|Genetics, 9(11), 3703–3714. doi: 10.1534/g3.119.400654.

Perks, K.M., Pierce, J.T. (2019). A quantal code for touch intensity in C. elegans. J Gen Physiol, 151(12), 1343. doi: 10.1085/jgp.201912477

Bainbridge, C., Clites, B.L., Caldart, C.S., Palacios, B., Rollins, K., Golombek, D.A., Pierce, J.T., Vidal-Gadea, A.G. (2019). Factors that influence magnetic orientation in Caenorhabditis elegans.J Comp Physiol A Neuroethol Sens Neural Behav Physiol, epub. doi: 10.1007/s00359-019-01364-y.

2018

Scott, L. L., Iyer, S., Philpo, A. E., Avalos, M. N., Wu, N. S., Shi, T., Prakash, B. A., Nguyen, T. T., Mihic, S. J., Aldrich, R. W., Pierce, J. T. (2018). A Novel Peptide Restricts Ethanol Modulation of the BK Channel In Vitro and In Vivo. Journal of Pharmacology and Experimental Therapeutics, 367(2), 282–290. https://doi.org/10.1124/jpet.118.251918

Pierce, J. T. (2018). Calnexin revealed as an ether-a-go-go chaperone by getting mutant worms up and going. The Journal of General Physiology, jgp.201812068. https://doi.org/10.1085/jgp.201812068

Scott, L. L., Sahn, J. J., Ferragud, A., Yen, R. C., Satarasinghe, P. N., Wood, M. D., Hodges, T. R., Shi, T., Prakash, B. A., Friese, K.M., Shen, A., Sabino, V., Pierce, J. T., Martin, S. F. (2018). Small molecule modulators of σ2R/Tmem97 reduce alcohol withdrawal-induced behaviors. Neuropsychopharmacology, 43(9), 1867–1875. https://doi.org/10.1038/s41386-018-0067-z

Mondal, S., Hegarty, E., Sahn, J. J., Scott, L. L., Gökçe, S. K., Martin, C., Ghorashian, N., Satarasinghe, P. N., Iyer, S., Sae-Lee, W., Hodges, T. R., Pierce, J. T., Martin, S. F., Ben-Yakar, A. (2018). High-Content Microfluidic Screening Platform Used To Identify σ2R/Tmem97 Binding Ligands that Reduce Age-Dependent Neurodegeneration in C. elegans SC_APP Model. ACS Chemical Neuroscience, 9(5), 1014–1026. https://doi.org/10.1021/acschemneuro.7b00428

Nordquist, S. K., Smith, S. R., & Pierce, J. T. (2018). Systematic Functional Characterization of Human 21st Chromosome Orthologs in Caenorhabditis elegans. G3 Genes|Genomes|Genetics, 8(3), 967-979. https://doi.org/10.1534/g3.118.200019

2017

Clites, B. L., & Pierce, J. T. (2017). Identifying Cellular and Molecular Mechanisms for Magnetosensation. Annual Review of Neuroscience, 40(1), 231–250. https://doi.org/10.1146/annurev-neuro-072116-031312

Scott, L. L., Davis, S. J., Yen, R. C., Ordemann, G. J., Nordquist, S. K., Bannai, D., & Pierce, J. T. (2017). Behavioral Deficits Following Withdrawal from Chronic Ethanol Are Influenced by SLO Channel Function in Caenorhabditis elegans . Genetics, 206(3), 1445–1458. https://doi.org/10.1534/genetics.116.193102

Yi, B., Sahn, J. J., Ardestani, P. M., Evans, A. K., Scott, L. L., Chan, J. Z., Iyer, S., Crisp, A., Zuniga, G., Pierce, J.T., Martin, S.F., Shamloo, M. (2017). Small molecule modulator of sigma 2 receptor is neuroprotective and reduces cognitive deficits and neuroinflammation in experimental models of Alzheimer’s disease. Journal of Neurochemistry, 140(4), 561–575. https://doi.org/10.1111/jnc.13917

Scott, L. L., Brecht, E. J., Philpo, A., Iyer, S., Wu, N. S., Mihic, S. J., Aldrich, R. W., Pierce, J., Walton, J. P. (2017). A novel BK channel-targeted peptide suppresses sound evoked activity in the mouse inferior colliculus. Scientific Reports, 7(1). https://doi.org/10.1038/srep42433

2015

Davis, S. J., Scott, L. L., Ordemann, G., Philpo, A., Cohn, J., & Pierce-Shimomura, J. T. (2015). Putative calcium-binding domains of theCaenorhabditis elegansBK channel are dispensable for intoxication and ethanol activation. Genes, Brain and Behavior, 14(6), 454–465. https://doi.org/10.1111/gbb.12229

Beron, C., Vidal-Gadea, A. G., Cohn, J., Parikh, A., Hwang, G., & Pierce-Shimomura, J. T. (2015). The burrowing behavior of the nematode Caenorhabditis elegans: a new assay for the study of neuromuscular disorders. Genes, Brain and Behavior, 14(4), 357–368. https://doi.org/10.1111/gbb.12217

Vidal-Gadea, A., Ward, K., Beron, C., Ghorashian, N., Gokce, S., Russell, J., … Pierce-Shimomura, J. (2015). Magnetosensitive neurons mediate geomagnetic orientation in Caenorhabditis elegans. eLife, 4. https://doi.org/10.7554/elife.07493

2014

Russell, J., & Pierce-Shimomura, J. T. (2014). Apparatus for investigating the reactions of soft-bodied invertebrates to controlled humidity gradients. Journal of Neuroscience Methods, 237, 54–59. https://doi.org/10.1016/j.jneumeth.2014.08.021

Davis, S. J., Scott, L. L., Hu, K., & Pierce-Shimomura, J. T. (2014). Conserved single residue in the BK potassium channel required for activation by alcohol and intoxication in C. elegans. Journal of Neuroscience, 34(29), 9562–9573. https://doi.org/10.1523/jneurosci.0838-14.2014

Russell, J., Vidal-Gadea, A. G., Makay, A., Lanam, C., & Pierce-Shimomura, J. T. (2014). Humidity sensation requires both mechanosensory and thermosensory pathways in Caenorhabditis elegans. Proceedings of the National Academy of Sciences, 111(22), 8269–8274. https://doi.org/10.1073/pnas.1322512111

Topper, S. M., Aguilar, S. C., Topper, V. Y., Elbel, E., & Pierce-Shimomura, J. T. (2014). Alcohol disinhibition of behaviors in C. elegans. PLoS ONE, 9(3), e92965. https://doi.org/10.1371/journal.pone.0092965

2013

Iyer, S., & Pierce-Shimomura, J. T. (2013). Worming Our Way to Alzheimer’s Disease Drug Discovery. Biological Psychiatry, 73(5), 396–398. https://doi.org/10.1016/j.biopsych.2012.12.026

Zlotkowski, K., Pierce-Shimomura, J., & Siegel, D. (2013). Small-Molecule-Mediated Axonal Branching inCaenorhabditis elegans. ChemBioChem, 14(3), 307–310. https://doi.org/10.1002/cbic.201200712

2012

Vidal-Gadea, A. G., & Pierce-Shimomura, J. T. (2012). Conserved role of dopamine in the modulation of behavior. Communicative & Integrative Biology, 5(5), 440–447. https://doi.org/10.4161/cib.20978

Alaimo, J. T., Davis, S. J., Song, S. S., Burnette, C. R., Grotewiel, M., Shelton, K. L., … Bettinger, J. C. (2012). Ethanol Metabolism and Osmolarity Modify Behavioral Responses to Ethanol inC. elegans. Alcoholism: Clinical and Experimental Research, 36(11), 1840–1850. https://doi.org/10.1111/j.1530-0277.2012.01799.x

Vidal-Gadea, A. G., Davis, S., Becker, L., & Pierce-Shimomura, J. T. (2012). Coordination of behavioral hierarchies during environmental transitions inCaenorhabditis elegans. Worm, 1(1), 5–11. https://doi.org/10.4161/worm.19148

2011

Vidal-Gadea, A., Topper, S., Young, L., Crisp, A., Kressin, L., Elbel, E., … Pierce-Shimomura, J. T. (2011). Caenorhabditis elegans selects distinct crawling and swimming gaits via dopamine and serotonin. Proceedings of the National Academy of Sciences, 108(42), 17504–17509. https://doi.org/10.1073/pnas.1108673108

2010

Speca, D. J., Chihara, D., Ashique, A. M., Bowers, M. S., Pierce-Shimomura, J. T., Lee, J., … McIntire, S. L. (2010). Conserved Role of unc-79 in Ethanol Responses in Lightweight Mutant Mice. PLoS Genetics, 6(8), e1001057. https://doi.org/10.1371/journal.pgen.1001057

Mesce, K.A. and Pierce-Shimomura, J. T. (2010). Shared strategies for behavioral switching: understanding how locomotor patterns are turned on and off. Frontiers in Behavioral Neuroscience. https://doi.org/10.3389/fnbeh.2010.00049

Schreiber, M. A., Pierce-Shimomura, J. T., Chan, S., Parry, D., & McIntire, S. L. (2010). Manipulation of Behavioral Decline in Caenorhabditis elegans with the Rag GTPase raga-1. PLoS Genetics, 6(5), e1000972. https://doi.org/10.1371/journal.pgen.1000972

2009

Kim, H., Pierce-Shimomura, J. T., Oh, H. J., Johnson, B. E., Goodman, M. B., & McIntire, S. L. (2009). The Dystrophin Complex Controls BK Channel Localization and Muscle Activity in Caenorhabditis elegans. PLoS Genetics, 5(12), e1000780. https://doi.org/10.1371/journal.pgen.1000780

2008

Pierce-Shimomura, J. T., Chen, B. L., Mun, J. J., Ho, R., Sarkis, R., & McIntire, S. L. (2008). Genetic analysis of crawling and swimming locomotory patterns in C. elegans. Proceedings of the National Academy of Sciences, 105(52), 20982–20987. https://doi.org/10.1073/pnas.0810359105

2006

Dunn, N. A., Pierce-Shimomura, J. T., Conery, J. S., & Lockery, S. R. (2006). Clustered Neural Dynamics Identify Motifs for Chemotaxis in Caenorhabditis elegans. In The 2006 IEEE International Joint Conference on Neural Network Proceedings. IEEE. https://doi.org/10.1109/ijcnn.2006.246730

2005

Pierce-Shimomura, J. T. (2005). Analysis of the effects of turning bias on chemotaxis in C. elegans. Journal of Experimental Biology, 208(24), 4727–4733. https://doi.org/10.1242/jeb.01933

2004

Dunn, N. A., Lockery, S. R., Pierce-Shimomura, J. T., & Conery, J. S. (2004). A Neural Network Model of Chemotaxis Predicts Functions of Synaptic Connections in the Nematode Caenorhabditis elegans. Journal of Computational Neuroscience, 17(2), 137–147. https://doi.org/10.1023/b:jcns.0000037679.42570.d5

2003

Davies, A. G., Pierce-Shimomura, J. T., Kim, H., VanHoven, M. K., Thiele, T. R., Bonci, A., … McIntire, S. L. (2003). A Central Role of the BK Potassium Channel in Behavioral Responses to Ethanol in C. elegans. Cell, 115(6), 655–666. https://doi.org/10.1016/s0092-8674(03)00979-6

2001

Pierce-Shimomura, J. T., Faumont, S., Gaston, M. R., Pearson, B. J., & Lockery, S. R. (2001). The homeobox gene lim-6 is required for distinct chemosensory representations in C. elegans. Nature, 410(6829), 694–698. https://doi.org/10.1038/35070575

1999

Pierce-Shimomura, J. T., Morse, T. M., & Lockery, S. R. (1999). The Fundamental Role of Pirouettes in Caenorhabditis elegans Chemotaxis. The Journal of Neuroscience, 19(21), 9557–9569. https://doi.org/10.1523/jneurosci.19-21-09557.1999

1997

Streichert, L. C., Pierce, J. T., Nelson, J. A., & Weeks, J. C. (1997). Steroid Hormones Act Directly to Trigger Segment-Specific Programmed Cell Death of Identified Motoneuronsin Vitro. Developmental Biology, 183(1), 95–107. https://doi.org/10.1006/dbio.1996.8467

Weeks, J. C., Jacobs, G. A., Pierce, J. T., Sandstrom, D. J., Streichert, L. C., Trimmer, B. A., … Wood, E. R. (1997). Neural Mechanisms of Behavioral Plasticity: Metamorphosis and Learning in Manduca sexta. Brain, Behavior and Evolution, 50(1), 69–80. https://doi.org/10.1159/000113356

Benjamin L. Clites , Ph.D. 1 , Hans  A.  Hofmann, Ph.D. 2 and  Jonathan T. Pierce,