The Colgin lab has published a paper in the journal Hippocampus entitled “The Relationship Between Gamma Frequency and Running Speed Differs for Slow and Fast Gamma Rhythms in Freely Behaving Rats”. This research investigates the way that different subtypes of gamma rhythms in the hippocampus correlate differently with rats’ behavior. Specifically, the frequency of fast gamma […]
Dr. Laura Colgin received a 5 year R01 grant from NIMH to study the roles of slow and fast gamma oscillations in memory processing. The proposed work will test the hypothesis that slow and fast gamma oscillations perform distinct functions in the hippocampal network, with fast gamma promoting memory encoding and slow gamma mediating memory retrieval.
The Raab-Graham lab recently published a research article in the journal Molecular Psychiatry entitled “Rapid Antidepressant Stimulates 14-3-3η Decoupling of GABABR from GIRK/Kir3″. For over 20 years it has been known that N-methyl-D-aspartate receptor (NMDAR) antagonists are effective as rapid antidepressants, however the underlying molecular mechanism of how NMDAR antagonists caused neuroadaptive changes in the brain […]
Congratulations to Dr. Rick Aldrich, who was elected as a Fellow of the American Association for the Advancement of Science (AAAS). The AAAS is an international non-profit organization dedicated to advancing science for the benefit of all people. Election as a Fellow of AAAS is an honor bestowed upon AAAS members by their peers. Fellows […]
Dr. Darrin Brager, in collaboration with Dr. Boris Zemelman, was awarded a new 5-year NIH R01 grant to study ion channels and dendrites in a mouse model of Fragile X syndrome.
Dr. Lewis-Peacock co-published a manuscript with Dr. Kenneth Norman (Princeton University) in Nature Communications entitled “Competition between items in working memory leads to forgetting”. Rapidly switching the focus of attention is believed to impair memory but it is unclear how. Lewis-Peacock and Norman use brain imaging and multivariate analysis to show that when two memories […]
Dr. Laura Colgin published a review paper in Current Opinion in Neurobiology entitled “Theta-gamma coupling in the entorhinal-hippocampal system”. Theta rhythms (∼5–10 Hz) have been thought to play a critical role in memory processing in the entorhinal–hippocampal network. However, recent evidence suggests that successful memory performance also requires coupling of ∼30–100 Hz gamma rhythms to particular phases […]
Michael Mack and Meg Schlichting, both members of the Preston Lab, were married in August. Michael wanted to give his bride-to-be a very special gift that represented his commitment and love, and given that they are both cognitive neuroscientists, that meant a 3-D model of his brain! The “thoughtful” gift even made the news! http://www.cnet.com/news/groom-gives-bride-heady-gift-his-brain/ […]
The Drew lab recently published research articles in the journal Learning & Memory and the journal Hippocampus. The Learning & Memory paper is entitled “Potent Attenuation of Context Fear by Extinction Training Contiguous with Acquisition”. This research investigated the mechanisms through which the emotional valence of a memory is established. Using a procedure known as contextual […]
The Raab-Graham lab recently published a research article in the journal Neurobiology of Disease entitled “Rapamycin reveals an mTOR-independent Repression of Kv1.1 Expression during Epileptogenesis”. This work investigates the changes in mTOR activity and resultant mTOR dependent regulation of Kv1.1 ion channel expression following epileptic activity. Sosanya N.M., Brager D.H., Wolfe S., Niere F. and […]